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According to the report, it is possible to co-exist with resistance by- developing new strategies to prevent resistance from spreading and, where it already exists, identify the strains we need to protect against; find new ways to treat resistance infections effectively in patients; and manage reservoirs of antibiotic strains in the environment. The report summarizes the current scientific understanding of antibiotic resistance, the scope of the problem, and methods at our disposal for detecting emergence and preventing spread. The knowledge gaps about the prevalence of resistant strains and resistant infections are highlighted as are the unique problems and challenges in developing countries.
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Prepared by Carol Nacy and Merry Buckley. People with Crohn’s disease (CD) are seven-fold more likely to have in their gut tissues the bacterium that causes a digestive-tract disease in cattle called Johne’s disease. The role this bacterium may or may not play in causing CD is a top research priority. This report points out that the cause of Crohn’s disease is unknown, and the possible role of this bacterium, which could conceivably be passed up the food chain to people, has received too little attention from the research community.
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Prepared by Merry Buckley.
This report details the study of pathogenesis and how far we have come to having a complete understanding of pathogenesis and a phylogenetic framework for understanding the phenomenon.
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Synthesizes conclusions reached by working groups at 1999 colloquium. Takes a broad view of the problem of increasing resistance to antimicrobials and its consequences for human, animal, and environmental health. Provides an overview of the current situation and offers specific recommendations for scientific research, surveillance programs, and education effor
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Prepared by James W. Snyder and William Check.
The Academy joined with the American College of Microbiology to examine the central roles of professional microbiologists and clinicians in recognizing the occurrence of possible bioterrorism events. Issues of medical laboratory and practitioner training, emergency preparedness plans, public education, collaboration, and communication across health care and law enforcement agencies from the local to the federal level are discussed.
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Prepared by Joan B. Rose, Anwar Huq, and Erin K. Lipp.
Takes a look at the combined advances in microbiology, meteorology, climatology, epidemiology, oceanography, ecology, medicine, and space science that are shedding light on the intricate connections between weather, oceans, and emerging and re-emerging diseases. Makes specific recommendations for future data collection, research collaboration, risk assessment, and the use of technology and molecular techniques.
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Prepared by Rita R. Colwell,and Jonathan A. Patz. Discusses research issues relating to the effects of climate on the incidence and distribution of infectious disease. Addresses specific infectious diseases and offers recommendations for future research.
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Prepared by Noel R. Rose.
Assesses the impact of current and future changes in health care on clinical microbiologists and the practice of clinical microbiology. Considers issues related to changes in patient demographics, technology, the work force, and the economic environment. Discusses the clinical microbiologist as consultant and educator.
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Prepared by Harriet L. Robinson, Harold S. Ginsberg, Heather L. Davis, Stephen A. Johnston, and Margaret A. Liu.
Provides in-depth analysis of relevant issues and outlines a strategy for funding and coordinating a massive research effort to increase knowledge about the mechanism of genetic immunizations and to identify potential applications.
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