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G. Adult and Pediatric Vaccine Studies and Pediatric Infections

 

Meet-the-Experts

 

Antibiotic Shortages, Antibiotic Stewardship and the Sick Child

Experts will introduce issues pertaining to antibiotic shortages and antibiotic stewardship that are of particular relevance to care of the sick child. Experts will provide an overview to guide attendees to understand current concerns and their basis. Ample time will be allotted for participation by attendees to clarify issues, add to the discussion and to pose questions.

Upon completion of this Meet-the-Experts Session, the participant should be able to:

• Discuss the basis for shortages of antibiotics employed in the care of sick children; and
• Apply principles of antibiotic stewardship relevant to the care of children. 

Experts:
Jason G. Newland, MD; Univ. of Missouri, Kansas City Sch. of Med. and Children’s Mercy Hosp., Kansas City, MO.
Mike Sharland, MD; St. George's Hosp., London, United Kingdom.

 

Healthy Mother, Healthy Baby

Those attending this session will be apprised of advances and promising developments prevention of HIV and influenza as these relate to maternal and child health. There will be ample opportunity for attendees to add comments, pose questions and interact with the experts.

Upon completion of this Meet-the-Experts Session, the participant should be able to:

• Cite important recent advances in prevention of perinatal transmission of HIV infection; and
• Discuss promising new strategies for prevention of influenza in pregnant women and young infants. 

Experts:
Claire Thorne, PhD; Univ. Coll. London, London, United Kingdom.
Saad B. Omer, MBBS, MPH, PhD; Emory Univ., Sch. of Publ. Hlth. & Med., Atlanta, GA.

 

Symposia

 

Hot Topics in Pediatric Infectious Disease: 2012

In this session, experts will present state-of-the-art advances in pediatric infectious diseases in lecture format. Time will be available after each presentation for questions from attendees and additional discussion.

Upon completion of this Symposium Session, the participant should be able to:

• Discuss contemporary advances in pathogenesis, diagnosis and treatment of key pediatric infectious diseases and their importance to child health;
• Summarize the potential impact of implementation of scientific advances to improve child health; and 
• Apply updated information to communication, decision-making and clinical practice. 

Conveners:
John S. Bradley, MD; Univ. of California San Diego Sch. of Med. & Rady Children’s Hosp., San Diego, CA.
Carlo Giaquinto, MD; Azienda Ospedaliera Univ., Padova, Italy.

Presentations:
TB or not TB? New Diagnostics and Treatment for Childhood TB
Jeffrey R. Starke, MD; Baylor Coll. of Med., Houston, TX.

New Insights into Shiga Toxin-Associated HUS
Marina Morigi, PhD; Mario Negri Inst. for Pharmacological Res., Bergamo, Italy.

HBV and HCV Treatment in Children
Giuseppe Indolfi, MD, PhD; Meyer Children’s Univ. Hosp. of Florence, Florence, Italy.

Challenges of MDR Gram-Negatives in Children
John S. Bradley, MD; Univ. of California San Diego Sch. of Med. & Rady Children’s Hosp., San Diego, CA.

 

Hot Topics in Vaccines

Each panelist will present important advances in vaccines from the current literature and will discuss their potential impact. Panelists will solicit comments and questions from conveners, other panelists and attendees. Hard copies of abstracts of the articles for discussion will be distributed to all attendees. Learners will be apprised of key developments in vaccine research and implementation as selected by leaders in this field of investigation.

Upon completion of this Symposium Session, the participant should be able to:

• Analyze the year’s important advances and biomedical discoveries in vaccinology;
• Assimilate the context of new scientific findings by discussion with experts in the field; 
• Anticipate the potential impact of discoveries on the prevention of infection; and 
• Plan strategies to apply new advances to further discovery or clinical practice. 

Conveners:
Sarah S. Long, MD; Drexel Univ. Coll. of Med., Philadelphia, PA.
Ron Dagan, MD; Ben-Gurion Univ. of the Negev and Soroka Univ. Med. Ctr., Beer-Sheva, Israel.

Presentations:
Carol J. Baker, MD; Baylor Coll. of Med., Houston, TX.
Kathleen Neuzil, MD, MPH; PATH, Seattle, WA.
Kathryn M. Edwards, MD; Vanderbilt Univ., Nashville, TN.
Jan Bonhoeffer, MD; Brighton Collaboration Fndn., Basel, Switzerland.

 

Interplay Between Pathogen and Host: From Immune Deficiency to Infectious Disease

Experts will highlight a number of cutting edge advances in pathogenesis as they relate to infectious diseases. Each expert will present newly discovered insights into mechanisms of infection and will discuss the impact of these findings upon clinical outcomes. Time will be allotted after each presentation for questions from those in attendance.

Upon completion of this Symposium Session, the participant should be able to:

• Discuss how immune activation adds to the challenges of treatment and prevention of HIV infection;
• Discuss new insights into immune reconstitution following treatment of immunodeficiencies; 
• Apply new insights into meningitis pathogenesis to evaluation and management of patients with meningitis; and 
• Identify advances in fungal infection pathogenesis in the immunodeficient host. 

Conveners:
Carlo Giaquinto, MD; Azienda Ospedaliera Univ., Padova, Italy.
Nigel J. Klein, MD, PhD; Inst. of Child Hlth., London, United Kingdom.

Presentations:
Immune Activation in HIV Infections
Andrew Predergast, MD; Queen Mary, Univ. of London, London, United Kingdom.

Immune Reconstitution Following Treatment of Immunodeficiencies
Nigel J. Klein, MD, PhD; Inst. of Child Hlth., London, United Kingdom.

New Insights into Meningitis Pathogenesis
Kwang Sik Kim, MD; Johns Hopkins Sch. of Med., Baltimore, MD.

Fungal Infection in the Immunodeficient Host
Emmanuel Roilides, MD; Aristotle Univ. Sch. of Med., Thessaloniki, Greece.

 

Vaccine Conquests and Challenges

Leaders in their fields of expertise will summarize state of the art advances in implementation, policy and/or goals for administration of several viral and bacterial vaccines with major impact upon health outcomes. Each speaker will allow time for discussion of questions posed by those in attendance.

Upon completion of this Symposium Session, the participant should be able to:

• Discuss the impact of expanded valent pneumococcal conjugate vaccines;
• Discuss the impact of implementation of meningococcal conjugate vaccines in specific locales; 
• Discuss the expected outcomes after introduction of HPV vaccines in boys; and 
• Discuss goals by region, impact of importation and challenges remaining in global measles control. 

Conveners:
Andrew J. Pollard, MD; Univ. of Oxford, Oxford, United Kingdom.
Janet A. Englund, MD; Univ. of Washington, Seattle, WA.

Presentations:
Pneumococcal Conjugates: Impact of Expanded Valent Vaccines
Anne Vergison, MD, PhD; ULB-HUDERF, Brussels, Belgium.

Meningococcal Conjugate Vaccines: North Africa and Beyond
Andrew J. Pollard, MD; Univ. of Oxford, Oxford, United Kingdom.

HPV Vaccine for Girls and Boys!
Janet A. Englund, MD; Univ. of Washington, Seattle, WA.

Global Measles: What's Next?
Jane F. Seward, MBBS, MPH; CDC, Atlanta, GA.

 

Vaccine Innovations

This symposium will summarize state-of-the-art progress in development of a universal influenza vaccine and vaccines for prevention of HIV-1 and Staphylococcus aureus infections. Each of these vaccines would impact health dramatically and on a global scale.

Upon completion of this Symposium Session, the participant should be able to:

• Discuss progress toward and challenges remaining to development of a vaccine to prevent HIV-1 infection;
• Discuss progress toward and challenges remaining to develop a prophylactic Staphylococcus aureus vaccine; and 
• Discuss progress toward and challenges remaining to realization of a universal vaccine for influenza. 

Convener:
Morven S. Edwards, MD; Baylor Coll. of Med., Houston, TX. 
Richard Koup, MD; NIH Vaccine Res. Ctr., Bethesda, MD.

Presentations:
Advances in Development of a Staphlococcus aureus Prophylactic Vaccine
Annaliesa S. Anderson, PhD; Pfizer Vaccine Res., Pearl River, NY.

A Universal Influenza Vaccine?
Wendy A. Keitel, MD; Baylor Coll. of Med., Houston, TX.

A Vaccine for HIV-1: Harnessing Cross-Reactive Antibodies
Richard Koup, MD; NIH Vaccine Res. Ctr., Bethesda, MD.

 

Interactive Symposium

 

Interactive Cases in Pediatric Infectious Diseases

The conveners will present a selection of challenging cases in pediatric infectious diseases. Conveners will solicit discussion from panelists as to differential diagnosis and approach to evaluation and management. Questions will be posed in the audience response format so that attendees can weigh-in as a measure of their personal diagnostic and therapeutic acumen. Conveners will prepare a brief summary of the important teaching points for each case presented.

Upon completion of this Interactive Symposium, the participant should be able to:

• Identify some common and not-so-common clinical manifestations of important infectious diseases in childhood;
• Cite medical evidence and current expert opinion in management and prevention of infections in childhood; 
• Assess and compare knowledge anonymously with peers; and 
• Recognize and identify unusual infectious diseases. 

Conveners:
Jeffrey R. Starke, MD; Baylor Coll. of Med., Houston, TX.
Karina M. Butler, MB, DCh; Our Lady’s Children’s Hosp., Dublin, Ireland.

Presentations:
Carol J. Baker, MD; Baylor Coll. of Med., Houston, TX.
Mary Anne Jackson, MD; Children's Mercy Hosp., Kansas City, MO.
David Isaacs, MD; The Children's Hosp., Westmead, Australia.
Anne Vergison, MD, PhD; ULB-HUDERF, Brussels, Belgium.
John S. Bradley, MD; Children's Hosp. and Hlth. Ctr., San Diego, CA.